4^th European Summit on Cardiology Research April 17-18, 2023 Paris, France

Biography:

Asma Amrani Midoun is affiliated to Biotechnology Department, Faculty of Sciences of Nature and Life, Medical Biochemistry and Molecular Biology Laboratory, Faculty of Medicine, University of Oran 1 Ahmed Benbella, Algeria.

 

 

Abstract:

Transition from wastewater treatment facilities as energy consumers to resource recovery facilities with ability to produce energy and value-added products is achievable by optimizing digestion capacity with the existing infrastructure. This study investigated a novel method for optimizing anaerobic digestion of multiple feedstocks for biomethane recovery. A series of experiments were conducted to develop an empirical model for optimizing the mixing ratio based on lipids, proteins and carbohydrates ratios of the feedstocks as compared to carbon to nitrogen (C:N) or COD to nitrogen ratio (COD:N). The selected feedstocks were real municipal wastes including dairy manure; Source Separated Organic (SSO) and Thickened Waste Activated Sludge (TWAS). The experimental data were fitted into the proposed second order polynomial model. The COD:N ratios of TWAS, manure and SSO were 15,47 and 27 respectively. For the co-digesters, COD:N varied from 19 to 40. The lipids:proteins:carbohydrates ratios were 1:10:4, 1:4:20 and 1:1.6:9 for TWAS, manure and SSO respectively. Among them SSO had the most ultimate methane production and methane yield corresponding to 1373 mL and 332 mL CH₄/g COD added. The minimum ultimate methane production and the methane yield occurred at TWAS mono digestion corresponding to the COD:N ratio of 15 and lipids: proteins: carbohydrates ratio of 1:10:4. The results indicated that both minimum ultimate methane and minimum methane yield values occurred at TWAS mono digestion corresponding to the COD:N ratio of 15 and lipids:proteins:carbohydrates ratio of 1:10:4. On the other hand, the maximum ultimate methane and methane yields occurred at the mixing ratios of 2:4:4 corresponding to the COD:N ratio of 28 and lipids:proteins:carbohydrates ratio of 1:3:12 in co-digestion of TWAS/manure/SSO.

 

Biography:

Samir Rafla , Alexandria University, Faculty of Medicine, Cardiology Department Egypt

Abstract:

Background: Guidelines allow stenting of unprotected left main coronary artery (LMCA) under special circumstances. Our study evaluated this subject without the utilization of IVUS. Methods: 120 patients with LMCA disease >50%. Exclusion criteria were Syntax score > 32 unless denied by the surgeon, cardiogenic shock and mechanically ventilated patients, patients with valvular heart disease requiring valve intervention, platelet count < 100000 or greater than 700000, or hemoglobin <10 g; recent major bleeding or current warfarin use; history of ischemic stroke within 6 months; patients with chronic total occlusion of a major epicardial vessel. The femoral approach in 101, radial in 19. LM stent type Xience Xpedition/ Alpine/V/Prime in 76 patients, in the remaining patients, other types of drug eluted stents were inserted. Results: 88 male patients and 32 females, mean age 61 years. 79% were diabetic, 69% hypertensive, 57% were current smokers, 50% were dyslipidemic.

Clinical presentation: 77% presented with acute coronary syndrome, 22.7% of them had previous PCI, one patient with previous CABG. 22.7% had chronic coronary syndrome (none of them had previous intervention). Angiographic (anatomical) characteristics: Distal lesion in 101 patients (94 bifurcation, 7 trifurcation), non-distal in 19. Ostial LCX significant disease in 50, none significant in 70. Bifurcation angle >70 in 28, < 70 i8n 92. Number of diseased vessels one in 19 patients, two in 65, three in 36. Presence of calcification in 55 patients.

Presence of thrombi in 39. RCA lesion in 29 patients. Medina classification (distal LM) 1.0.0 in 11; 0.1.0 in 0; 1.1.0 in 33; 0.0.1 in 0; 1,0,1 in 12; 0.1.1 in 0; 1,1,1 in 45 patients. Syntax score < 23 in 17 patients; 23-32 in 73; >32 in 29 patients. Residual Syntax < 0-24 + 6. Complications: Access hematoma 8 (6.6%), PCI dissection 2 (1.66%). CIN (Contrast Induced Nephropathy) in 3 (2.5%); Heart Failure in 7 (5.8%). Mortality none. CABG referral none. Follow up for 6 months: Death 2 (1.7%), non-fatal ACS 6 (5%), stroke 1 (0.8%). Conclusions: PCI in unprotected left main coronary artery disease is a safe and feasible option with a high technical success rate and acceptable outcome in follow-up. Risk stratification is critical for strategy selection in the management of LMCAD patients. The absence of Assisting imaging techniques namely IVUS is not prohibitive in this contest despite its valuable role in stent optimization.