Coronary Artery Disease & Vascular Biology

Coronary artery disease (CAD) remains a leading cause of morbidity and mortality worldwide, driven by atherosclerosis and endothelial dysfunction. Understanding vascular biology, plaque composition, and inflammatory mechanisms is critical for prevention and treatment. Advances in molecular imaging, biomarkers, and genetic profiling enhance early detection and risk assessment. Interventional techniques, including PCI with drug-eluting stents and bioresorbable scaffolds, restore perfusion while minimizing complications. Pharmacological strategies targeting lipid metabolism, inflammation, and thrombosis improve clinical outcomes. Emerging therapies, such as regenerative vascular therapy and endothelial modulation, aim to restore vessel integrity. Lifestyle interventions, personalized nutrition, and digital monitoring complement medical treatments. AI-driven predictive models enhance early identification of high-risk patients and guide therapeutic decisions. Multidisciplinary approaches integrating cardiology, vascular medicine, and rehabilitation optimize recovery and reduce recurrence. Research continues to focus on precision-targeted interventions, novel pharmacotherapies, and innovative imaging modalities, reflecting the evolving landscape of coronary and vascular health management.

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